Calcium antagonists for aneurysmal subarachnoid haemorrhage

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Calcium antagonists for aneurysmal subarachnoid haemorrhage.

BACKGROUND Secondary ischaemia is a frequent cause of poor outcome in patients with subarachnoid haemorrhage (SAH). Its pathogenesis has been incompletely elucidated, but vasospasm probably is a contributing factor. Experimental studies have suggested that calcium antagonists can prevent or reverse vasospasm and have neuroprotective properties. OBJECTIVES To determine whether calcium antagoni...

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BACKGROUND The timing of surgery to secure a ruptured aneurysm after a subarachnoid haemorrhage is an important issue. Early clipping of an aneurysm prevents rebleeding, a major cause of death after a subarachnoid haemorrhage. However, concerns about the possible deleterious effects of early surgery raise questions about the safety and efficacy of this approach. This review examines the randomi...

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Neurosurgical management of aneurysmal subarachnoid haemorrhage

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The initial CT scans of 76 patients with aneurysmal subarachnoid haemorrhage were reviewed, and the amount of blood visible in the basal CSF cisterns was quantified. The outcome of surgery was found to correlate significantly with the quantity of blood seen on the scan, as did the pre-operative grade of the patient, a history of pre-existing hypertension, and the presence of angiographic vasosp...

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Aneurysmal subarachnoid haemorrhage from a neuroimaging perspective

Neuroimaging is a key element in the management of patients suffering from subarachnoid haemorrhage (SAH). In this article, we review the current literature to provide a summary of the existing neuroimaging methods available in clinical practice. Noncontrast computed tomography is highly sensitive in detecting subarachnoid blood, especially within 6 hours of haemorrhage. However, lumbar punctur...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2007

ISSN: 1465-1858

DOI: 10.1002/14651858.cd000277.pub3